Peptide Compass
Explore/PYY 3-36 (Peptide YY 3-36)

PYY 3-36 (Peptide YY 3-36)

Fat Loss / Metabolic • Peptide

◐ Emerging EvidenceInvestigational
Evidence
Moderate4/10
Hype
Low3/10
Risk
Low2/10
Beginner Friendly
Moderate4/10

Plain English Summary

PYY 3-36 is a peptide hormone that plays a key role in regulating appetite and energy balance. It is a truncated form of peptide YY, primarily secreted by the intestine after feeding, and is involved in satiety, reducing food intake, and potentially impacting insulin sensitivity and gut motility.

What People Use It For

Weight LossAppetite SuppressionImproved Glycemic Control

Side Effects & Risks

Common Side Effects

Gastrointestinal discomfortNauseaVomitingPotential malaise-like effectsPossible gastrointestinal-related adverse events

References

  • 1https://pubmed.ncbi.nlm.nih.gov/28003328/
  • 2https://pubmed.ncbi.nlm.nih.gov/40629530/
  • 3https://pubmed.ncbi.nlm.nih.gov/37572954/
  • 4https://pubmed.ncbi.nlm.nih.gov/37001706/
  • 5https://pubmed.ncbi.nlm.nih.gov/38542814/
  • 6https://pubmed.ncbi.nlm.nih.gov/25527432/
  • 7https://pubmed.ncbi.nlm.nih.gov/26006332/
  • 8https://pubmed.ncbi.nlm.nih.gov/12167864/

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Educational Content Only

This is not medical advice. Always consult a licensed healthcare provider before using any compound. No dosing or sourcing guidance is provided.